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KMID : 0351219920240010045
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Korean Journal of Infectious Diseases
1992 Volume.24 No. 1 p.45 ~ p.54
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A Case of Q Fever : Associated with pancytopenia, Hepatitis and Myocarditis
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박효숙
이은경/이승렬/유철주/손영모/김동수/김길영/이원영
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Abstract
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Q fever is an acute (on occasion chronic) febrile illness caused by in halation of Coxiella burnetii, and usually manifest as a self-limited febrile illness, pneumonia, endocarditis, hepatitis, skin rashes, myocarditis, pleuropericarditis,
osteomyelitis, neurologic disease, hematologic disease, or infertility and spontaneous abortion. Treatment with tetracycline, trimethoprim-sulfamethoxazole, doxycycline, or quinolone has been effective.
We experienced a case of Q fever in a 5-year-old female patient. She complained of prolonged fever, abdominal pain and arthralgia of both knee or admission. She developed hepatitis, myocarditis, congestive heart failure, hepatosplenomegaly,
pancytopenia, bone marrow necrosis and disseminated intravascular coagulation. Peripheral blood cell culture revealed Coxiella burnetii and hairy cells and antibody titer to phase I antigen was 1:160 by indirect immunofluorescent antibody assay.
After
intravenous chloramphenicol and oral rifampin, above symptoms and complications were improved.
We presented a case of Q fever with a review of literatures.
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KEYWORD
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